Triglycerides

Leading Insights: A Conversation with Professors Gerald Watts and Ioanna Gouni-Berthold

October 25, 2026

Watch the newest episode of IAS’ Leading Insights series to learn from Prof. Gerald Watts and Prof. Ioanna Gouni-Berthold as they discuss the results of SHASTA-3 and SHASTA-4. These clinical trials evaluated plozasiran, a hepatocyte-targeted siRNA that reduces hepatic APOC3 synthesis, in patients with severe hypertriglyceridemia.

IAS received unrestricted support from Arrowhead Pharmaceuticals to develop this resource.

About Leading Insights
Leading Insights is a video series in which IAS’ global experts discuss recent research findings about breakthrough diagnostic tools, therapies and devices relevant to the diagnosis and management of atherosclerosis and related cardiometabolic diseases.

Promoting the scientific understanding of atherosclerosis

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