Triglycerides
Treating Severe Hypertriglyceridemia and Reducing the Risk of Pancreatitis
November 9, 2026
This new infographic defines severe hypertriglyceridemia (sHTG) and shows how plozasiran, a hepatocyte-targeted siRNA, reduces hepatic APOC3 synthesis. It also notes the impact of plozasiran on lowering triglycerides and acute pancreatitis events as demonstrated in the SHASTA-3 and SHASTA-4 trials. These studies are discussed in the Leading Insights episode with Professors Ioanna Gouni-Berthold and Gerald Watts.
Promoting the scientific understanding of atherosclerosis
Newsletters
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The IAS e-Newsletter is a digest of the latest from the IAS and its Constituent Member Societies.
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Going beyond statins, this resource provides the latest information about primary prevention for clinicians.
